Development and manufacturing of sprays

Sprays are a widely used treatment option for ENT (ear, nose, and throat) ailments, combining precise dosage, ease of use, and targeted efficacy close to the mucous membranes.

Volume_Filling (2)
Material: PET, PE, HDPE or glass vials coated with a PE film, oval or round
Volume_Filling (1)
Filling volume: 5 to 30 ml
solutions supensions
Formulations: liquid solutions, slightly viscous liquids, and suspensions.
Sprays
Stérile
Clip-on dosing pump or nebulizer cannula, screw cap
personnalisation
Inkjet printing, single and double labeling
statut
Statuses: Medical device, medication, homeopathy, veterinary

Advantages of the technology

Choosing a spray means choosing precision, simplicity, and targeted efficacy.

  • In-line sterilization of the solution by 0.2µm sterilizing filtration
  • Turnkey products, from concept to finished product
  • A multidisciplinary and international team to meet all your regulatory, development, or manufacturing needs
  • Various packaging options: size, format, and material

The list of molecules compatible with our ENT solutions continues to expand, including: xylometazoline, seawater, isotonic saline solutions, beclomethasone, mometasone, melatonin, naphazoline, dexamethasone, oxymetazoline, and carragelose.

Manufacturing sites and capacity

Out-licensing - our turnkey documentation and products in Blow-Fill-Seal (BFS) packaging

 Table: Out-licensing - our turnkey documentation and products in Blow-Fill-Seal (BFS) packaging
Spray Volume Category Status Dossier Country
Carragelose - Nasal spray for colds for children over one year old, 1.2 mg/ml 20 ml Cough and Cold MD (IIa) CE marking in transition N Contact us
Carragelose - Throat spray for adults and children from 1 year old, 1.2 mg/ml 20 ml Cough and Cold MD (IIa) CE marking in transition N Contact us

End-to-end support from the initial phases: from concept to product

Manufacturing

From technology transfer to industrial manufacturing, from small clinical batches to commercial volumes.

Development

Formulation and analytical development, manufacture of clinical batches, stability studies, and expertise in ophthalmic development.

Out-licensing

Access medicines and medical devices that are ready to be registered and marketed.

Got questions? - Consult our FAQ

We primarily offer BFS (Blow-Fill-Seal), liquid stick packs, sprays, and multi-dose vials.

No. The program is also open to medical devices or combined products, depending on the project.

Yes. Our services are modular: formulation, analytics, clinical manufacturing, regulatory support.

CMC regulatory support ensures your product and processes remain compliant with health authority requirements (EMA, FDA, ANVISA, etc.) throughout their lifecycle. At Unither, this support is provided by a dedicated regulatory affairs team within the Development, Quality, and Production teams. The service ensures the drafting and submission of dossiers (IMPD/IND, CTD/eCTD) goes smoothly, facilitates communication with authorities, and assists with post-authorization stages: variations, renewals, and audits.