{"id":31676,"date":"2026-02-03T18:08:57","date_gmt":"2026-02-03T17:08:57","guid":{"rendered":"https:\/\/www.unither-pharma.com\/publication\/developpement-dun-produit-ophtalmique-depuis-la-phase-early-stage\/"},"modified":"2026-03-18T16:09:52","modified_gmt":"2026-03-18T15:09:52","slug":"%e8%81%9a%e7%84%a6%e7%9c%bc%e7%a7%91%e4%ba%a7%e5%93%81%e5%bc%80%e5%8f%91%ef%bc%9acdmo-unither-%e5%a6%82%e4%bd%95%e5%9c%a8%e6%97%a9%e6%9c%9f%e9%98%b6%e6%ae%b5%ef%bc%88early-stage%ef%bc%89%e9%99%aa","status":"publish","type":"publication","link":"https:\/\/www.unither-pharma.com\/zh-hans\/publication\/%e8%81%9a%e7%84%a6%e7%9c%bc%e7%a7%91%e4%ba%a7%e5%93%81%e5%bc%80%e5%8f%91%ef%bc%9acdmo-unither-%e5%a6%82%e4%bd%95%e5%9c%a8%e6%97%a9%e6%9c%9f%e9%98%b6%e6%ae%b5%ef%bc%88early-stage%ef%bc%89%e9%99%aa\/","title":{"rendered":"\u805a\u7126\u773c\u79d1\u4ea7\u54c1\u5f00\u53d1\uff1aCDMO Unither 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data-end=\"469\">\u4e3a\u66f4\u597d\u5730\u54cd\u5e94\u65e9\u671f\u9636\u6bb5\u9879\u76ee\uff08early-stage\uff09\u7684\u9700\u6c42\uff0cUnither \u8fd1\u5e74\u6765\u6301\u7eed\u63a8\u8fdb\u81ea\u8eab\u7ed3\u6784\u5316\u5efa\u8bbe\uff1a<br data-start=\"315\" data-end=\"318\" \/>\u4e00\u65b9\u9762\u5f3a\u5316\u7814\u53d1\u56e2\u961f\uff0c\u53e6\u4e00\u65b9\u9762\u62d3\u5c55\u6cd5\u89c4\u4e8b\u52a1\u670d\u52a1\uff08\u5305\u62ec\u6cd5\u89c4\u7b56\u7565\u652f\u6301\u3001\u6ce8\u518c\u6587\u4ef6\u7684\u64b0\u5199\u4e0e\u51c6\u5907\u7b49\uff09\u3002\u540c\u65f6\uff0cUnither \u8fd8\u5728\u6cd5\u56fd\u3001\u7f8e\u56fd\u548c\u4e2d\u56fd\u7684\u6240\u6709 Blow-Fill-Seal\uff08BFS\uff09\u751f\u4ea7\u57fa\u5730\u6301\u7eed\u63d0\u5347\u4ea7\u80fd\uff0c\u5e76\u901a\u8fc7\u4e24\u9879\u65b0\u6280\u672f\u62d3\u5c55\u4ea7\u54c1\u7ec4\u5408\uff1a<strong data-start=\"433\" data-end=\"446\">\u65e0\u9632\u8150\u5242\u591a\u5242\u91cf\u7cfb\u7edf<\/strong>\uff08\u6cd5\u56fd\uff09\u548c<strong data-start=\"451\" data-end=\"464\">\u542b\u9632\u8150\u5242\u591a\u5242\u91cf\u7cfb\u7edf<\/strong>\uff08\u5df4\u897f\uff09\u3002<\/p>\n<p data-start=\"471\" data-end=\"553\">\u5f97\u76ca\u4e8e\u8fd9\u4e00\u4ee5\u201c\u5f3a\u5316\u5f00\u53d1\u80fd\u529b\u201d\u4e3a\u6838\u5fc3\u7684\u6218\u7565\uff0cUnither \u4f5c\u4e3a CDMO\uff0c\u5df2\u6210\u4e3a\u773c\u79d1\u4ea7\u54c1\u5f00\u53d1\u9886\u57df\u7684\u91cd\u8981\u53c2\u4e0e\u8005\uff0c\u4e3a\u751f\u7269\u6280\u672f\u516c\u53f8\u3001\u521d\u521b\u4f01\u4e1a\u53ca\u836f\u7269\u5f00\u53d1\u516c\u53f8\u63d0\u4f9b\u5168\u6d41\u7a0b\u652f\u6301\u3002<\/p>\n<h2 data-start=\"560\" data-end=\"576\"><\/h2>\n<h2 data-start=\"560\" data-end=\"576\">\u5ba2\u6237\uff1a\u63a8\u52a8\u884c\u4e1a\u53d8\u9769\u7684\u53c2\u4e0e\u8005<\/h2>\n<p data-start=\"578\" data-end=\"733\">Unither \u7684\u5ba2\u6237\u7fa4\u4f53\u65e2\u5305\u62ec\u521d\u521b\u4f01\u4e1a\uff0c\u4e5f\u5305\u62ec\u751f\u7269\u6280\u672f\u516c\u53f8\u548c\u5236\u836f\u7814\u53d1\u4f01\u4e1a\u3002\u4e0d\u4ec5\u9650\u4e8e\u5f00\u53d1\u5168\u65b0\u773c\u79d1\u5206\u5b50\u7684\u4e2d\u5c0f\u578b\u516c\u53f8\uff0c\u4e5f\u6db5\u76d6\u4e13\u6ce8\u4e8e\u773c\u75c5\u6cbb\u7597\u7684\u6210\u719f\u5236\u836f\u4f01\u4e1a\uff0c\u751a\u81f3\u5305\u62ec\u5df2\u7ecf\u62e5\u6709\u591a\u5242\u91cf\u6216\u5355\u5242\u91cf\u6ef4\u773c\u6db2\u4ea7\u54c1\u7684\u516c\u53f8\u3002\u6b64\u5916\uff0c\u5728\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u4e34\u5e8a\u7814\u7a76\u7ec4\u7ec7\uff08CRO\uff09\u4e5f\u5f80\u5f80\u53c2\u4e0e\u5176\u4e2d\uff0c\u7531\u4e8e\u704c\u88c5\u64cd\u4f5c\u7684\u4fbf\u5229\u6027\uff0c\u76f8\u5173\u7814\u7a76\u901a\u5e38\u5728\u5c0f\u578b\u73bb\u7483\u74f6\u4e2d\u5b8c\u6210\u3002<\/p>\n<p data-start=\"735\" 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data-end=\"881\">\u5bf9\u4e8e\u4e3a\u671f\u4e00\u4e2a\u6708\u7684\u957f\u671f\u6cbb\u7597\uff0c\u591a\u5242\u91cf\u5305\u88c5\u901a\u5e38\u66f4\u4e3a\u5408\u9002\uff1b<\/p>\n<\/li>\n<li data-start=\"882\" data-end=\"920\">\n<p data-start=\"884\" data-end=\"920\">\u800c\u5355\u5242\u91cf\u5219\u66f4\u9002\u7528\u4e8e\u77ed\u671f\u6216\u9636\u6bb5\u6027\u6cbb\u7597\uff08\u4f8b\u5982\u672f\u540e\u7528\u836f\uff09\u6216\u4e2d\u7b49\u4f7f\u7528\u9891\u7387\u7684\u60c5\u51b5\u3002<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"922\" data-end=\"1091\">\u5728 Unither\uff0c\u5ba2\u6237\u53ef\u4ee5\u5728 <strong data-start=\"938\" data-end=\"949\">BFS \u5355\u5242\u91cf<\/strong> \u4e0e <strong data-start=\"952\" data-end=\"963\">\u65e0\u9632\u8150\u5242\u591a\u5242\u91cf<\/strong> \u4e4b\u95f4\u81ea\u7531\u9009\u62e9\u3002\u6700\u7ec8\u7684\u6280\u672f\u8def\u5f84\uff0c\u901a\u5e38\u4f1a\u968f\u7740\u9879\u76ee\u5728\u4e34\u5e8a\u9636\u6bb5\u7684\u63a8\u8fdb\u800c\u9010\u6b65\u660e\u786e\u3002\u4f8b\u5982\uff0c\u5728\u5242\u91cf\u63a2\u7d22\u7814\u7a76\uff08dose ranging study\uff09\u8fc7\u7a0b\u4e2d\uff0c\u5ba2\u6237\u5c06\u786e\u5b9a\u4ea7\u54c1\u6d53\u5ea6\u3001\u6bcf\u65e5\u6ef4\u7528\u6b21\u6570\u53ca\u6cbb\u7597\u5468\u671f\uff08\u5373\u7ed9\u836f\u65b9\u6848\uff09\u3002\u6b63\u662f\u5728\u8fd9\u4e00\u9636\u6bb5\uff0c\u5ba2\u6237\u4f1a\u51b3\u5b9a\u91c7\u7528 BFS \u8fd8\u662f\u591a\u5242\u91cf\u5bb9\u5668\u3002<\/p>\n<h2 data-start=\"1098\" data-end=\"1110\"><\/h2>\n<h2 data-start=\"1098\" data-end=\"1110\">\u836f\u7269\u5f00\u53d1\u7684\u5173\u952e\u9636\u6bb5<\/h2>\n<p data-start=\"1112\" data-end=\"1225\">\u5236\u836f\u4f01\u4e1a\u901a\u5e38\u4e86\u89e3\u5982\u4f55\u4e3a\u65b0\u836f\u51c6\u5907\u5e76\u5411\u536b\u751f\u76d1\u7ba1\u673a\u6784\u63d0\u4ea4\u6ce8\u518c\u8d44\u6599\uff0c\u4f46\u672a\u5fc5\u719f\u6089\u5728\u6ef4\u773c\u6db2\uff08BFS \u6216\u591a\u5242\u91cf\uff09\u5f00\u53d1\u8fc7\u7a0b\u4e2d\u6240\u9700\u5f00\u5c55\u7684\u5404\u7c7b\u7814\u7a76\u548c\u6d4b\u8bd5\u3002\u5bf9\u4e8e\u5b66\u672f\u673a\u6784\u6216\u5c0f\u578b\u7814\u53d1\u516c\u53f8\u800c\u8a00\uff0c\u8fd9\u4e00\u5dee\u8ddd\u66f4\u4e3a\u660e\u663e\uff0c\u56e0\u4e3a\u4ed6\u4eec\u5f80\u5f80\u5c1a\u672a\u5411\u76d1\u7ba1\u673a\u6784\u63d0\u4ea4\u8fc7\u6ce8\u518c\u7533\u62a5\u3002<\/p>\n<p data-start=\"1227\" data-end=\"1326\">\u4e3a\u5e2e\u52a9\u8fd9\u4e9b\u5ba2\u6237\u66f4\u597d\u5730\u7406\u89e3\u5e76\u987a\u5229\u63a8\u8fdb\u6ce8\u518c\u6d41\u7a0b\uff0cUnither \u5236\u5b9a\u4e86\u4e00\u5957\u6e05\u6670\u7684\u6d41\u7a0b\u793a\u610f\u56fe\uff0c\u7cfb\u7edf\u68b3\u7406\u4e86\u4ece\u4e34\u5e8a\u524d\u9636\u6bb5\uff08\u56fe\u4e2d\u79f0\u4e3a\u201c\u9884\u914d\u65b9\u7814\u7a76\u201d\uff09\u5230\u5de5\u4e1a\u5316\u653e\u5927\u751f\u4ea7\uff08\u201c\u653e\u5927\u4e0e\u5de5\u4e1a\u5316\u201d\uff09\u6240\u9700\u5f00\u5c55\u7684\u5404\u9879\u6d4b\u8bd5\u4e0e\u7814\u7a76\u3002<\/p>\n<p data-start=\"1328\" data-end=\"1449\">\u76ee\u524d\uff0cUnither \u6b63\u5728\u8ba8\u8bba\u4e2d\u7684\u7ea6 <strong data-start=\"1347\" data-end=\"1359\">15 \u4e2a\u5f00\u53d1\u9879\u76ee<\/strong> \u8986\u76d6\u4ece\u4e34\u5e8a\u9636\u6bb5\u5230 III \u671f\u4e34\u5e8a\uff0c\u6d89\u53ca\u6ce2\u5c14\u591a\u3001\u5e93\u5510\u65af\u3001\u7f57\u5207\u65af\u7279\u548c\u4e9a\u7720\u7b49\u751f\u4ea7\u57fa\u5730\u3002\u5176\u4e2d\uff0c\u6709 <strong data-start=\"1405\" data-end=\"1418\">3 \u81f3 4 \u4e2a\u9879\u76ee<\/strong> \u5904\u4e8e\u6ce2\u5c14\u591a\u7684\u9884\u5f00\u53d1\u9636\u6bb5\uff0c\u672a\u6765\u5c06\u8f6c\u79fb\u81f3 BFS \u5de5\u5382\u8fdb\u884c\u751f\u4ea7\u3002<\/p>\n<p data-start=\"1451\" data-end=\"1557\">\u4e3a\u652f\u6301\u4e0a\u8ff0\u670d\u52a1\uff0cUnither \u5728\u5404\u751f\u4ea7\u57fa\u5730\u5747\u8bbe\u7acb\u4e86\u4e13\u7528\u4e8e\u5f00\u53d1\u7684\u4e2d\u8bd5\u8f66\u95f4\u548c\/\u6216\u79fb\u52a8\u5f0f\u751f\u4ea7\u7f50\uff0c\u7528\u4e8e\u4e34\u5e8a\u6279\u6b21\u548c\u6280\u672f\u6279\u6b21\u7684\u751f\u4ea7\u3002Unither \u8d85\u8fc7 30 \u5e74\u7684\u4e13\u4e1a\u7ecf\u9a8c\u4e0e\u6280\u672f\u79ef\u7d2f\uff0c\u4e5f\u4e3a\u8fd9\u4e9b\u6d3b\u52a8\u7684\u987a\u5229\u5f00\u5c55\u63d0\u4f9b\u4e86\u575a\u5b9e\u4fdd\u969c\u3002<\/p>\n<h2 data-start=\"1564\" data-end=\"1581\"><\/h2>\n<h2 data-start=\"1564\" data-end=\"1581\">\u7075\u6d3b\u6027\uff1a\u4ece\u5c0f\u6279\u91cf\u5230\u5927\u89c4\u6a21\u751f\u4ea7<\/h2>\n<p data-start=\"1583\" data-end=\"1681\">\u5bfb\u6c42 BFS 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data-end=\"1763\">\u4f8b\u5982\uff1a<\/p>\n<ul data-start=\"1764\" data-end=\"1884\">\n<li data-start=\"1764\" data-end=\"1825\">\n<p data-start=\"1766\" data-end=\"1825\">\u5728 <strong data-start=\"1768\" data-end=\"1784\">Coutances \u5de5\u5382<\/strong>\uff0c\u65e2\u53ef\u751f\u4ea7 <strong data-start=\"1790\" data-end=\"1797\">3 \u5347<\/strong>\u7684\u5c0f\u6279\u91cf\uff0c\u4e5f\u53ef\u5b9e\u73b0 <strong data-start=\"1807\" data-end=\"1818\">2,000 \u5347<\/strong>\u7684\u5927\u6279\u91cf\uff1b<\/p>\n<\/li>\n<li data-start=\"1826\" data-end=\"1884\">\n<p data-start=\"1828\" data-end=\"1884\">\u5728 <strong data-start=\"1830\" data-end=\"1846\">Rochester \u5de5\u5382<\/strong>\uff0c\u6700\u5c0f\u6279\u91cf\u4e3a <strong data-start=\"1853\" data-end=\"1864\">25\u201330 \u5347<\/strong>\uff0c\u6700\u5927\u540c\u6837\u53ef\u8fbe <strong data-start=\"1872\" data-end=\"1883\">2,000 \u5347<\/strong>\u3002<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1886\" 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